An estimated 720,598 people in Missouri live with migraine.

Based on U.S. Census ACS 2023 population data and Burch et al. (2021) migraine-specific prevalence rates.

Census ACS 2023 · Burch et al. (2021) · CC BY 4.0

Patient Population by Care Level

How many patients need each level of care.

32,850
need specialist or headache program care
Complexity Levels 1–2*
122,085
need neurology-level care
Complexity Levels 3–4*
565,665
appropriate for primary care
Complexity Level 5*

* Care level estimates are based on a proposed patient complexity framework offered as a basis for clinical and policy discussion. See methodology →

By Congressional District

8 congressional districts in Missouri

DistrictTotal patientsSpecialist care*Neurology care*Primary care*
MO-03101,2054,61517,14279,446
MO-0199,0974,52016,78777,791
MO-0598,7554,50516,73477,521
MO-0795,6544,36216,20375,091
MO-0893,7004,26715,87873,563
MO-0693,3504,25215,81973,277
MO-0489,3724,07615,14070,153
MO-0288,7984,04515,04269,702

* Care level estimates are based on a proposed patient complexity framework offered as a basis for clinical and policy discussion. See methodology →

Headache Centers & Programs

2 headache centers and programs in Missouri

Headache Centers — Level 1

Freeman Neurology & Headache Clinic

Joplin, MO

2 providers · 1 UCNS-certified

freemanhealth.com/staff/gulshan-uppal

Hope Headache and Neurology

Lake Saint Louis, MO

2 providers · 2 UCNS-certified

www.hhneuro.com/aboutus

Provider counts reflect headache program providers only — not all neurologists at the same address. UCNS certification verified against the United Council for Neurologic Subspecialties diplomate directory.

More Data Coming

Building a complete picture.

Coming September 2026

Payer Policy Data

What insurers in Missouri require before authorizing CGRP-targeting therapies — step therapy requirements, formulary placements, and Gold Card law status.

Coming Fall 2026

Prescribing Gap Analysis

How many primary care physicians actively treating migraine patients in Missouri have never prescribed a CGRP-targeting therapy — by metro area and congressional district.

Doty A. Missouri Headache Disorder Population Estimates. The Headache Vault; 2026. headachevault.com/research/states/missouri Licensed CC BY 4.0.
✓ CC BY 4.0
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